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In 2015-2018 I was a postdoc in the Program in Applied and Computational Mathematics at Princeton University, working with Amit Singer.
Also see this paper about the properties of DNA and sequencing.
Long-Range "Independence" The repetitive nature of DNA strings is one of the challenges in read alignment.
The movie below is an example of a reconstruction of a continuously heterogeneous object, using the approach described in this paper.
This is one of several approaches that I am developing for the heterogeneity problem in cryo-EM, and for other aspects of cryo-EM. See project webpage, this paper and in this report.
We propose a new approach to read alignment using random permutations of strings.
Results We present a prototype implementation and experiments performed with simulated and real reads of human DNA.
I am also a member of the Quantitative Biology Institute (QBio) at Yale.
I am an Assistant Professor at the Department of Statistics and Data Science at Yale University.